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KMID : 0032220110230010101
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Annals of Dermatology
2011 Volume.23 No. 1 p.101 ~ p.103
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A Case of Metastatic Squamous Cell Carcinoma Arising from Actinic Cheilitis
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Kwon Na-Hyun
Kim Si-Yong
Kim Gyong-Moon
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Abstract
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Actinic keratosis (AK) is a common, sun-induced, pre- malignant lesion with a strong likelihood of progressing to a malignancy. The reported risk of AK progressing to squamous cell carcinoma (SCC) varies from less than 1% to 20%. Clinically, induration, pain, large size, marked hyperkeratosis, ulceration, bleeding, rapid growth, and recurrence or persistence may be markers of AK progression into SCC. The risk of SCC metastasizing ranges between 0.5% and 3%. However, SCC of the lip arising from actinic cheilitis is more prone to metastasis than cutaneous SCC, with rates of the former varying between 3% and 20%. Here we report a typical case of SCC from actinic cheilitis with metastasis to the lymph nodes during a 4-year follow-up period. To exclude SCC, we emphasize the need for regular follow-up and prompt evaluation, including careful pathologic examination for actinic cheilitis.
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KEYWORD
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Actinic cheilitis, Squamous cell carcinoma
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